QurCan’s proprietary TERP technology has been engineered with a novel Polymer-Lipid surface chemistry to direct therapeutic payloads to tissue beyond the liver, including CNS and spleen. TERP technology can effectively transport nucleotides including mRNA and siRNA into the cells there they are active.
TERP is a breakthrough technology with the great potential to deliver a new era of disease-modifying genetic medicine that will make a difference to patients with a wide range of unmet medical needs.
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Selective Tissue Targeting With a library of components, the TERP nanoparticles can be customized to deliver payloads to the target tissues selectively. |
Excellent Safety Profile The non-immunogenic and biocompatible TERP formulation, allows repeated dosing of biologicals at high therapeutic doses. |
Payload Versatility The unique properties of TERP chemistry allows loading a wide range of payloads, including RNAs, peptides & antibodies, and small molecules. |
TERP PLATFORM FACILITATES DRUG PENETRATION INTO THE BRAINThe CNS-Specific TERP technology facilitates active blood-brain-barrier (BBB) penetration via dual-specific transport pathways. Validated in various pre-clinical disease models, TERP significantly increases brain penetration of therapeutics. The technology offers high degree of flexibility to accommodate various payloads (mRNAs, siRNA, small molecules, peptides and antibodies). |
